| << Previous 1 - 2 Next >> |
What Is Sickle Cell Disease?
Sickle cell disease is an inherited blood disorder, passed down through genes from one’s birth parents.iv
With sickle cell disease, the body cannot make healthy hemoglobin, a vital protein in red blood cells that delivers oxygen throughout the body.i While healthy red blood cells are round and move through small blood vessels to deliver oxygen, red blood cells for those with sickle cell disease are damaged and become hard, sticky, and look like a C-shape, or a “sickle.” iv, vThese sickled red blood cells die early and can get stuck, clogging blood flow in the blood vessels.iv, vi
Individuals with sickle cell disease often experience periodic episodes of extreme pain, known as pain crises, due to this blocked blood flow.v Along with extreme pain, this can lead to other lifelong issues like infection, stroke, and even organ failure,vi sometimes leading to an early death.vii
Sickle cell affects an estimated 100,000 people in the U.S. and is most common among people of African, Hispanic, Middle Eastern, and South East Asian descent, who oftentimes face inequities when seeking care.viii
What Types of Challenges Do Patients with Sickle Cell Disease Face?
Often, people with sickle cell disease have significant health problems that may result in unpredictable pain episodes and frequent healthcare visits, and many face health-related stigma and racial bias when seeking care.ix For example, patients with sickle cell often wait 25% longer than other emergency room patients before receiving care,x and Black patients are 22% less likely to receive pain medication for any condition compared to white patients.xi
They can even be mislabeled as “drug seekers” because the symptoms of the disease are largely invisible to the naked eye.xii Sometimes these sudden, excruciating pain episodes can last up to 11 days on average.xiii However, some doctors and nurses do not believe the severity of their pain.xiv
Additionally, many people with sickle cell do not have access to the specialized care they need, despite the disease’s devastating impacts. Without access to specialists, a symptom-focused approach to care can lead healthcare providers, who typically are not specialists, to overlook the root cause of the disease.viii
According to Dr. Kim Smith-Whitley, Medical Affairs Lead for Sickle Cell Disease at Pfizer, healthcare teams with expertise in providing sickle cell-related care are often hard to find because they are uncommon. Because of this, support systems for people with sickle cell are very important. “Patients, like Makenzie, and caregivers must become advocates to find the right medical team to work with them to maximize their health and partner with them to find the best treatment approach,” says Dr. Smith-Whitley.
But advocacy doesn’t stop at finding the right medical team. “Challenges like transportation to medical appointments, limited access to mental healthcare, and difficulty navigating the healthcare system can make an already isolating experience even harder,” she continues. These barriers can prevent patients from getting the care they need, especially when living with a condition that often goes unseen. Dr. Smith-Whitley encourages patients and caregivers to seek out community-based organizations and resources that can help ease these burdens.
Closing the care gap for people living with sickle cell disease takes more than good intentions; it takes partnership, persistence, and a willingness to reimagine what support can look like. That’s where Pfizer is leaning in. Through its Patient Engagement team, Pfizer is helping support the fight against sickle cell disease, working hand-in-hand with patients, caregivers, and advocates to help break down barriers to care.
Whether it’s supporting non-profit organizations to help ease the burden of travel to healthcare appointments or scholarship programs to help empower eligible individuals with sickle cell to pursue their academic and vocational goals, Pfizer’s goal is simple: meeting individuals with sickle cell where they are and supporting the fight against sickle cell disease.
Why Is Proactive Care for Sickle Cell Important?
For far too long, innovation in this space has lagged—particularly for more proactive care and education to help manage symptoms and increase longevity.v Dr. Smith-Whitley believes that taking a more proactive approach to care provides the opportunity for patients and caregivers to focus on decreasing the likelihood of complications such as the sudden onset of unpredictable pain and certain bacterial infections.viThis includes partnering with your healthcare team to explore options to decrease sickle cell-related complications.
“Sickle cell care needs to go beyond just managing pain crises as they happen,” says Dr. Smith-Whitley. “Effective, proactive care and education could help patients reclaim control and allow them to enjoy more of life’s precious moments.”
When living with sickle cell disease, it is crucial to find strength in the community, consider a proactive approach to care, and stay informed about the latest advancements. Makenzie has learned this through lived experience. Diagnosed with sickle cell at birth, she grew up surrounded by the support of her family and a dedicated healthcare team. Her parents encouraged her to pursue all of her passions—cheering, singing, dancing, even softball and volleyball. Makenzie never let the disease determine her limits. Over time, she came to understand not only how to manage her condition but how to speak up for herself and take control of her health.
After transitioning out of pediatric care, Makenzie found herself stepping into a new kind of independence—going to appointments by herself without her parents or long-time healthcare team by her side. It wasn’t easy, but the process taught her the importance of finding a care team that listens, builds trust, and takes her condition seriously. Most of all, this shift pushed her to advocate for herself and take a more proactive role in her long-term health.
Makenzie’s journey with sickle cell didn’t just shape her. From a young age, she was fascinated by the world of healthcare, often pretending to be a nurse with a toy stethoscope in one hand and a wide range of questions for doctors at her appointments. But it was living with sickle cell day after day, dealing with uncertainty, and learning how to manage her condition that turned her childhood curiosity into her inspiration for pursuing a career choice. Now, Makenzie is studying to become a nurse, inspired by her journey and hoping to one day support others living with sickle cell the way her care team supported her.
“Be your own advocate” is a phrase that’s become Makenzie’s guiding principle. For her, comprehensive care isn’t just about managing pain; Makenzie is proof that sickle cell disease may shape someone’s path—but it doesn’t have to define it.
And through cross-industry collaboration, the hope is that other people living with sickle cell disease can have a similar reality. “Our work isn’t finished,” says Dr. Smith-Whitley. “Through continued research, resources, and support programs for people living with sickle cell, Pfizer’s commitment to the sickle cell community goes beyond medicine. We strive to meet people where they are—fighting to ensure they feel seen, heard, and empowered through every step of their journey.”
Learn more about Pfizer’s continued commitment to sickle cell and access additional resources at pfizersicklecellcommitment.com.
PP-LTV-USA-3391 November 2025
March is National Kidney Month, a time when communities across the country raise awareness about kidney disease. This year’s focus is on taking charge of your health and the many factors that go into managing your kidney disease.
Chronic kidney disease (CKD) is a serious condition affecting 37 million people. Often overlooked until symptoms appear, CKD is progressive and can put you at risk for serious health complications including kidney failure. Adopting a healthy lifestyle can help you manage and slow progression of CKD and its complications.
Follow these healthy lifestyle tips to take charge of your kidney health.
It may seem difficult, but small changes can go a long way to keeping your kidneys and you healthier for longer.
This year alone, more than 280,000 Americans will be diagnosed with prostate cancer. During National Prostate Cancer Awareness Month, we honor the lives ended too soon and all those we can still save by redoubling our efforts to end cancer as we know it.
When someone is diagnosed with prostate cancer, every second counts. But patients are too often left advocating for basic care while drowning in a flood of medical information. Even when treatment is available, some struggle to afford it or insurance may not cover it. And stark inequities exist: Black men are more than twice as likely to die from prostate cancer in this country than other men.
Our Nation must do more to change that. Last year, the First Lady and I reignited the Cancer Moonshot, setting an ambitious new goal to cut America’s cancer death rate by at least half over the next 25 years, turning more cancers from death sentences into treatable diseases and improving support for patients and families. I worked with the Congress to establish the Advanced Research Projects Agency for Health, securing $2.5 billion in bipartisan funding to develop breakthroughs in preventing, diagnosing, and treating cancer and other deadly diseases and pioneering partnerships to get those breakthroughs out to clinics and patients. We are making lifesaving cancer care more affordable for millions of Americans, expanding coverage through Medicaid and the Affordable Care Act, and helping many who had received relief during the pandemic to keep saving $800 a year on insurance premiums. The Inflation Reduction Act will soon cap total out-of-pocket prescription drug costs for seniors on Medicare at $2,000 a year — including for expensive cancer medicines — which could save some prostate cancer patients up to $6,000 a year.
We are also working to make sure prevention, detection, and treatment procedures are available to patients of all communities and backgrounds. The National Institutes of Health is continuing expansive research into environmental and genetic factors to better understand why prostate cancer disproportionately affects Black men. In response to our Cancer Moonshot, the Department of Veterans Affairs expanded its National Precision Oncology Program to better tailor treatments to individual veterans. And we know that screening matters: Experts recommend that men with a higher risk of cancer — based on race or ethnicity, family history, or other factors — discuss it with their doctors.
Everyone’s journey with cancer is different, but the First Lady and I know how hard it can be on the whole family. To all those caring for loved ones with prostate cancer and all those facing it themselves, we stand with you. My Administration is working around the clock on breakthroughs that can bring hope and more choices to the fight against this disease.
NOW, THEREFORE, I, JOSEPH R. BIDEN JR., President of the United States of America, by virtue of the authority vested in me by the Constitution and the laws of the United States, do hereby proclaim September 2023 as National Prostate Cancer Awareness Month. I encourage citizens, government agencies, private businesses, nonprofit organizations, and other interested groups to join in activities that will increase awareness of what Americans can do to prevent and cure prostate cancer.
IN WITNESS WHEREOF, I have hereunto set my hand this thirty-first day of August, in the year of our Lord two thousand twenty-three, and of the Independence of the United States of America the two hundred and forty-eighth.
JOSEPH R. BIDEN JR.
1 Feb 2021 — 4 min read
Jul. 23, 2019 - July is National Minority Mental Health Awareness Month, which was established in 2008 to bring awareness to the unique struggles that underrepresented groups in the United States face regarding mental illness. Clearly, mental health conditions do not discriminate based on race, color, or gender identity, yet we see stark differences in access to, and utilization of, treatment resources. Approximately 1 in 5 adults in the U.S. (46.6 million) experiences mental illness in a given year, regardless of their race.1 Fewer than half of adults in the U.S. with a mental health condition receive mental health services in a given year. African Americans however, utilize mental health services at about one-half the rate of Caucasian Americans.2 This begs the question: why?
We cannot rule out the impact of historical adversity, which has led to race-based exclusion from health, educational, social and economic resources. Many African Americans today still feel the socioeconomic impact of slavery, sharecropping, and Jim Crowism. Socioeconomic status is linked to mental health, in that people who are impoverished, homeless, or incarcerated are at higher risk for poor mental health. We also cannot rule out the impact of stigma associated with mental illness in the African American community. According to the Health and Human Services Office of Minority Health, African-Americans are 20% more likely to experience serious mental health problems than the general population, yet African Americans are less likely to initiate treatment and more likely to end treatment prematurely.
Literature suggests that African Americans are much more likely to rely on their faith as a coping mechanism for dealing with depression and anxiety than they are to utilize a mental health professional. One study found that 90.4% of African Americans reported use of religious coping in dealing with mental health issues.3 In other words, many African Americans, rather than seeking support in the form of a mental health professional, go to the church.
This is not surprising when one understands the traditional role of the African American Church. There has always been a connection to faith and the emotional well-being of African Americans. I can remember personally, sitting on the front pew of the church, the son of a pastor, watching in awe as my father recited spirited sermons from the pulpit as the congregation hung on every word. After church it seemed that everyone wanted to get close to him. There was something about connection with the faith leader that brought a sense of comfort and familiarity. There has always been an intersection of faith & freedom. It was faith that sustained our African ancestors through slavery. Whether it’s in terms of freedom from physical bondage, spiritual bondage, or mental bondage, faith has been viewed as the key to unlock the shackles. Within the African American community, there was often a belief that no matter how great the burden, prayer was the answer.
The African American church has traditionally been the gateway into the African American community. It has been our access to social services, family counseling, and a sense of belonging. African American faith leaders also play a pivotal role in community messaging about what is important to black & brown people. We have historically looked to our faith leaders for political guidance, and to be the spokesperson when our communities have needed a champion. As stigma is a significant barrier to accessing the needed support and care for individuals facing mental health concerns, the ability for individuals in distress to have a conversation with a trusted faith leader with whom they have a shared history is often an essential component. It is imperative that our faith leaders are equipped to respond appropriately to the lack of mental health resources in our communities while removing barriers to care.
Our faith leaders can play a pivotal role, if we are to move the needle on improving mental wellness in the African American community. My use of the term “wellness” is intentional; a crucial first step in changing the narrative is to change the language. We should focus on wellness rather than “illness.” Illness implies that something is wrong. Wellness lends itself more easily to viewing treatment as preventive.
If we want to strengthen the role of the church in promoting metal wellness, we must:
The topic of mental health is still often associated with a sense of shame among African Americans, making it hard for those experiencing distress to reach out for help, and for those who care about them to help connect them to that help. By spreading awareness and understanding about suicide prevention and mental health, the church can become an important place of refuge for those struggling.
Overview
Heart attacks and strokes can be catastrophic, life-changing events that are all too common. Heart disease and strokes are preventable, yet they remain the leading causes of death, disability, and healthcare spending in the US. Alarmingly, many of these events happen to adults ages 35-64—over 800,000 in 2016. Million Hearts® is a national initiative with a network of partners focused on preventing one million heart attacks, strokes, and other cardiovascular events by 2022. Coordinated actions by public health and healthcare professionals, communities, and healthcare systems can and will keep people healthy, optimize care, and improve outcomes within priority populations.
* Deaths, hospitalizations, and emergency room visits due to heart attack, stroke, and other cardiovascular conditions like heart failure that could be prevented if Million Hearts 2022 actions are taken.
People not taking aspirin as recommended.
People with uncontrolled blood pressure.
Adults not using statins (cholesterol-lowering medicines) when indicated.
Adult smokers.
Adults who are physically inactive.
Source: Million Hearts® At-A-Glance, 2017

In 2016, about 775,000 hospitalizations and 75,000 deaths occurred in younger Americans, who are America’s workforce, parents, partners, and caregivers.
Everyone can take small steps to improve their own health, the health of their families and loved ones, patients, communities, and the heart health of our nation. We have to act now.
View large image and text description
One million events could be prevented by 2022 if every state reduced these life-changing events by 6%.
While rates are higher in the Southeast and Midwest, small changes to improve heart health are needed in all states.
The solution to this crisis is already in front of us. Small changes sustained over time will result in big improvements to the heart health of our nation. Everyone can take action.
Million Hearts® is working with more than 120 partners, all 50 states and the District of Columbia, and 20 federal agencies to:
Keep people healthy by making changes to environments in which people live, learn, work, and play to make it easier to make healthy choices.
HOW: Achieve a 20% reduction in sodium intake, tobacco use, and physical inactivity.
Communities making physical activity easier by creating walking and biking trails.
People adding 10 minutes of physical activity a day—like walking or gardening.
Optimize care so that those at risk for cardiovascular disease get services and skills needed to reduce the risk of having a heart attack or stroke.
Improve outcomes for priority populations who suffer more from cardiovascular disease and where we know we can make an impact.
Keeping People Healthy.
Optimizing Care.
Improving Outcomes for Priority Populations—People who have had a heart attack or stroke.

More information about Million Hearts® and tools you can use are available at millionhearts.hhs.govExternal.
Stories from people who have taken control of their blood pressure are available at https://bit.ly/2N9ahqXExternal.
Heart disease doesn’t happen just to older adults. It is happening to younger adults more and more often. This is partly because the conditions that lead to heart disease are happening at younger ages.
February is American Heart Month, the perfect time to learn about your risk for heart disease and the steps you need to take now to help your heart.
Heart disease—and the conditions that lead to it—can happen at any age.
High rates of obesity and high blood pressure among younger people (ages 35–64) are putting them at risk for heart disease earlier in life.
Nearly half of all Americans have at least one of the top three risk factors for heart disease: high blood pressure, high cholesterol, and smoking.1,2
Learn about your risk for heart disease and the steps you need to take now to help your heart.
Many of the conditions and behaviors that put people at risk for heart disease are appearing at younger ages:
On average, U.S. adults have hearts that are 7 years older than they should be. Watch this video to learn about “heart age.”
Other conditions and behaviors that affect your risk for heart disease include:
You’re in the driver’s seat when it comes to your heart. Learn how to be heart-healthy at any age.
Don’t smoke. Smoking is the leading cause of preventable death in the United States. If you don’t smoke, don’t start. If you do smoke, learn how to quit.
Manage conditions. Work with your health care team to manage conditions such as high blood pressure and high cholesterol. This includes taking any medicines you have been prescribed. Learn more about preventing and managing high blood pressure and high cholesterol.
Make heart-healthy eating changes. Eat food low in trans fat, saturated fat, added sugar, and sodium. Try to fill at least half your plate with vegetables and fruits, and aim for low sodium options. Learn more about how to reduce sodium.
Stay active. Get moving for at least 150 minutes per week.11 You can even break up the exercise into 10-minute blocks for a total of 30 minutes in a day. Learn more about how to get enough physical activity.
CDC
National Heart, Lung, and Blood Institute
American Heart Association

Breast cancer can have different symptoms for different people. Most don’t notice any signs at all.
The most common symptom is a lump in your breast or armpit. Others include skin changes, pain, a nipple that pulls inward, and unusual discharge from your nipple.
Common symptoms of breast cancer include:
There are several kinds of breast cancer. Many of them share symptoms.
Symptoms of ductal carcinoma
This is the most common type of breast cancer. It begins in your ducts. About 1 in 5 new breast cancers are ductal carcinoma in situ (DCIS). This means you have cancer in the cells that line your ducts, but it hasn’t spread into nearby tissue.
You may not notice any symptoms of ductal carcinoma. It can also cause a breast lump or bloody discharge.
Symptoms of lobular carcinoma
This kind begins in the glands that make milk, called lobules. It’s the second most common type of breast cancer. Symptoms include:
Symptoms of invasive breast cancer
Breast cancer that’s spread from where it began into the tissues around it is called invasive or infiltrating. You may notice:
Symptoms of metastatic breast cancer
Without treatment, breast cancer can spread to other parts of your body, including other organs. This is called metastatic, advanced, or secondary breast cancer. Depending on where it is, you may have:
Symptoms of triple-negative breast cancer
Breast cancer is called triple-negative if it doesn’t have receptors for the hormones estrogen and progesterone and doesn’t make a lot of a protein called HER2. This kind tends to grow and spread faster than other types, and doctors treat it differently.
Triple-negative tumors make up 10% to 15% of breast cancers. They cause the same symptoms as other common types.
Symptoms of male breast cancer
About 1% of breast cancers happen in men. Because it’s so rare, you may not pay attention to the symptoms until the cancer has grown. Watch for:
Symptoms of Paget’s disease of the breast
This type often happens along with ductal carcinoma. It affects the skin of your nipple and areola. Symptoms may look like eczema and include:
Symptoms of inflammatory breast cancer (IBC)
Inflammatory breast cancer is a rare type that causes symptoms similar to an infection. They include:
Symptoms of papillary carcinoma
This is a very rare type of ductal cancer. It’s named for the tiny lumps, or papules, on the tumor. Common symptoms include:
Symptoms of angiosarcoma
Fewer than 2% of breast cancers are angiosarcomas. These start in the cells that line your blood vessels or lymph nodes. Angiosarcoma may cause:
Breast lumps are common and usually aren’t cancer. Other conditions that can cause them include:
Talk to your doctor if you notice any kind of lump in your breast or armpit. Get medical care as soon as possible if you also have signs of an infection such as redness, swelling, or discharge.
Breast cancer can come back, or recur, long after treatment. It may be in the same breast (local), in the lymph nodes near the original cancer (regional), or in a part of your body that’s farther away (metastatic or distant).
Cancer is most likely to come back in the first 2 years after treatment. After that period, the risk goes down over time.
Your doctor will talk with you about what to watch for. Local symptoms include:
Mastectomy and surgery to replace a breast (reconstruction) may lead to a buildup of scar tissue or fat cells. These lumps aren’t cancer. But it’s important to let your doctor know about them and watch for changes.
Symptoms of regional recurrence include:
Symptoms of metastatic recurrence depend on what body part is affected. The most common places are your bones, lungs, brain, and liver. You may have:
| << Previous 1 - 2 Next >> |